Keywords: Myocardium, Heart, Bright- and black blood imaging, T1/T2 mapping
Motivation: Cardiovascular MR (CMR) provides comprehensive assessment of heart disease. However, conventional CMR examinations involve multiple sequential 2D acquisitions under breath-hold conditions.
Goal(s): To devise and develop a novel 3D free-breathing sequence for simultaneous assessment of cardiovascular anatomy via bright- and black-blood imaging and myocardial tissue quantification in a single scan.
Approach: Implementation of an improved iNAV-based 5-heartbeat interleaved sequence (proACTION) with distinct IR and T2 preparation modules and non-rigid motion correction for robust and accurate myocardial tissue quantification.
Results: proACTION provides accurate delineation of cardiac and vascular structures, while demonstrating good agreement with conventional mapping sequences in healthy subjects.
Impact: Comprehensive 3D whole-heart tissue characterization and clinically relevant anatomical information can be obtained in an efficient, free-breathing, and easier to use one-click-scan with the proposed proACTION approach.
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