Abstract #0683

Free-breathing respiratory-navigator-gated 2D radial MR fingerprinting of the transplanted heart at 3T.

Pauline Calarnou¹, Augustin C. Ogier¹, Tamila Abdurashidova², Jean-Baptiste Ledoux^3,4, Jérôme Yerly^3,4, Roger Hullin², and Ruud B. Van Heeswijk³

¹Radiology, Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, Lausanne, Switzerland, ²Cardiology Service, Cardiovascular Department, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, Lausanne, Switzerland, ³Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland, Lausanne, Switzerland, ⁴CIBM Center for BioMedical Imaging, Lausanne and Geneva, Switzerland, Lausanne, Switzerland

Synopsis

Keywords: Myocardium, Transplantation

Motivation: To acquire T₁, T₂ and ECV maps in heart transplant recipients using a free-breathing technique that minimizes through-plane motion.

Goal(s): To characterize a free-breathing 2D joint T₁/T₂ cardiac MR fingerprinting technique named PARMA that includes a lung-liver navigator in the patient setting.

Approach: We compared the resulting maps to gold standard maps in a phantom and to clinical routine maps in 10 healthy volunteers and 9 heart transplant recipients.

Results: We found high accuracy in the phantom and high precision in the volunteers and heart transplant recipients.

Impact: This work demonstrates the feasibility of a free-breathing 2D joint T1/T2 MR fingerprinting in a heart transplant recipient population that cannot always perform long breath holds. The navigator allows a free breathing acquisition with limited through-plane motion.

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