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Abstract #0686

Accelerated T1ρ,adiab Mapping using Slice Selective Spin-Lock Preparation Pulses (FAST1ρ)

Andrew Tyler1, Karl Kunze2, Radhouene Neji1, Pier Giorgio Masci1, Amadeo Chiribiri1, and Sébastien Roujol1
1Biomedical Engineering and Imaging Science, King's College London, London, United Kingdom, 2MR Research Collaborations, Siemens Healthcare Limited, Camberly, United Kingdom

Synopsis

Keywords: Myocardium, Relaxometry

Motivation: T1ρ mapping is a promising non-contrast technique for the assessment of myocardial scar. Myocardial T1ρ mapping techniques commonly acquire multiple images in one breath hold to calculate a single-slice T1ρ map. Recently, non-selective adiabatic pulses have been employed for spin-lock preparation (T1ρ,adiab). FAST1ρ provides a two-fold acceleration for multi-slice myocardial T1ρ,adiab mapping.

Goal(s): To assess the T1ρ,adiab map quality of FAST1ρ compared to a single-slice 2D T1ρ,adiab mapping sequence.

Approach: 10 healthy-volunteers were scanned with FAST1ρ and a single-slice sequence.

Results: FAST1ρ had no significant difference in intra-subject variability or subject-wise precision, to the single-slice sequence, and successfully visualized a myocardial scar.

Impact: FAST1ρ provides a two-fold acceleration for multi-slice myocardial T1ρ,adiab mapping. It has no significant difference in intra-subject variability or subject-wise precision, compared to a single-slice sequence, and shows promise for characterization a myocardial scar.

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Keywords