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Abstract #0816

Development of a cross-modality tissue-mimicking and anatomic mimicking Fetal Phantom to improve image based fetus assessment

Remi Hattat1, Mariela Zambrano2, Zhongzheng He1, Erwan Bozec3, Mbaimou Auxence Ngremmadji1, Marine Beaumont1,2, Olivier Morel1,4, Gaëlle Ambroise Grandjean1,4, and Bailiang Chen1,2
1INSERM U1254, IADI, University of Lorraine, Vandoeuvre les Nancy, France, 2CIC-IT 1433, CHRU Nancy, Vandoeuvre les Nancy, France, 3CIC-P 1433, CHRU Nancy, Vandoeuvre les Nancy, France, 4Maternité Régionale de Nancy, Vandoeuvre les Nancy, France

Synopsis

Keywords: Fetal, Phantoms, Fetus, Biometrics, Tissue mimicking, Cross-modality imaging

Motivation: Fetal MRI necessitates extra care due to inherent safety concerns, complicating the optimization of MRI protocols and calibration with ultrasound assessments.

Goal(s): To mitigate the aforementioned safety problems, we aim to create a cross-modality, tissue-mimicking, anatomically correct fetal phantom.

Approach: We designed a fetus phantom encapsulated within a natural rubber balloon filled with mimicking amniotic fluid, creating an amniotic sac analogue. This design utilized varying compositions of agarose, gadolinium, and gelatin to replicate different fetal organs with distinct T1 and T2 values.

Results: The developed phantom comprises various fetal organs and relaxation times, enabling precise fetal biometric comparisons between MRI and ultrasound modalities.

Impact: With the help of the developped cross-modality, tissue-mimicking and anatomical mimicking fetus phantom, the aforementioned constraints on fetal MR protocol optimization and calibration between different MR and ultrasound should be relaxed.

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Keywords