Keywords: Fetal, Fetus, model-based recontruction; T2* mapping; QSM
Motivation: Quantitative $$$T_{2}^{*}$$$ and susceptibility mapping is of great interest for fetal MRI. While conventional EPI-based approaches are efficient, they usually suffer from motion and field distortion artifacts.
Goal(s): To develop a distortion-free and motion-robust quantitative $$$T_{2}^{*}$$$ and susceptibility mapping approach for fetal brain.
Approach: A stack-of-star multi-echo FLASH sequence and model-based reconstruction were developed for quantitative mapping of $$$T_{2}^{*}$$$ and $$$B_{0}$$$ of fetal brain. Motion estimation and correction is incorporated into the reconstruction to reduce motion artifacts.
Results: Initial findings indicate accurate $$$T_{2}^{*}$$$ measurements. Motion-corrected image reconstruction effectively minimized motion artifacts. Fetal $$$T_{2}^{*}$$$ and $$$B_{0}$$$ maps are obtained with reasonable quantitative $$$T_{2}^{*}$$$ values.
Impact: Our technique enables distortion-free and motion-robust quantitative $$$T_{2}^{*}$$$ and $$$B_{0}$$$ mapping for the fetal brain, utilizing a stack-of-star multi-echo acquisition and model-based reconstruction. It has the potential to address motion and field distortion artifacts typically encountered in EPI-based methods.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords