Abstract #0850

Developing a body composition protocol on a commercial 0.55T MRI system

Rebecca E Thornley^1,2, Zihan Ning^1,3, Brandon Whitcher⁴, Philippa Bridgen^1,2,3, Jimmy D Bell⁴, E Louise Thomas⁴, Sharon L Giles^1,2, Claire J Steves^2,5, Sebastien Ourselin¹, Joseph V Hajnal^1,3, and Anthony N Price^1,2,3

¹Biomedical Engineering Department, School of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom, ²Guy’s and St Thomas’ NHS Foundation Trust, London, United Kingdom, ³Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King’s College London, London, United Kingdom, ⁴Research Centre for Optimal Health, School of Life Sciences, University of Westminster, London, United Kingdom, ⁵Department of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

Synopsis

Keywords: Screening, Low-Field MRI, Body Composition

Motivation: Body composition MRI is well established at 1.5T. However there is limited work at low-field where there is growing interest, particularly with increased accessibility of ultra-wide bore systems.

Goal(s): Demonstrate the feasibility of body composition MRI on a 0.55T (80cm) system, and present optimised sequence parameters suitable for large-scale studies.

Approach: Dixon and liver T1 and T2*/PDFF scans were optimised iteratively by scanning subjects with a range of BMIs at 0.55T using ultra-flexible receive-array coils.

Results: Body composition MRI has been demonstrated on a commercial 0.55T system. Image quality was sufficient for utilisation of an analysis pipeline established for higher field.

Impact: Body composition MRI is feasible on a commercial 0.55T system, providing motivation for further protocol development. This generation of scanner presents an opportunity for more affordable and accessible MRI, with a wide bore suitable for imaging larger patients and participants.

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