Keywords: New Trajectories & Spatial Encoding Methods, Data Acquisition
Motivation: Several diseases influence the human vocal fold oscillation which can currently only be studied with superficial stroboscopic imaging.
Goal(s): We aim to develop a technique that allows the full characterization of the vocal fold oscillation with sub-millisecond sub-millimeter resolution.
Approach: ZTE MRI allows to freeze sub-ms dynamic signal changes in k-space. With synchronization data from a microphone, we retrospectively gate ZTE MRI data of the larynx acquired during singing using a total variation constraint in the time domain to reconstruct the vocal fold motion.
Results: 3D vocal fold oscillations can be visualized with ultra-high spatial (0.8mm) and temporal (670μs) resolution.
Impact: This work aims to improve the understanding of the VF oscillation under various physiological and pathological conditions, and might have applications in 3D dynamic MRI of other oscillatory body motions.
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