Abstract #1096

High-Resolution Reduced FOV Renal Chemical Exchange Saturation Transfer MRI Using orthogonal RF pulses

Qianqian Zhang^1,2, Zelong Chen³, Zhigang Wu⁴, Kan Deng⁵, Quan Tao^2,6, Wenyan Zhang^1,2, Yizhe Zhang^1,2, Yikai Xu³, and Yanqiu Feng^1,2

¹School of Biomedical Engineering, Southern Medical University, Guangzhou, China, ²Guangdong Provincial Key Laboratory of Medical Image Processing & Guangdong Province Engineering Laboratory for Medical Imaging and Diagnostic Technology, Southern Medical University, Guangzhou, China, ³Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China, ⁴Philips Healthcare, Shenzhen, China, ⁵Philips Healthcare, Guangzhou, China, ⁶Department of Rehabilitation, Zhujiang Hospital, Southern Medical University, Guangzhou, China

Synopsis

Keywords: CEST / APT / NOE, CEST & MT

Motivation: Long scanning time and low resolution limit the chemical exchange saturation transfer (CEST) clinical translation.

Goal(s): We aimed to develop a high-resolution renal reduced field of view CEST (rCEST) technique to reduce scanning time.

Approach: The rFOV based on orthogonal RF pulses in combination with conventional CEST module was performed on a volunteer and compared this technique with full-size FOV CEST (fCEST).

Results: Compared to fCEST, rCEST has shorter scanning time, higher image quality, and better saturation efficiency at the same image resolution.

Impact: The rCEST technique may have potential for clinical applications requiring high resolution and metabolic renal CEST-MR image.

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