Keywords: Arrhythmia, Tissue Characterization, ventricular tachycardia, catheter ablation
Motivation: Catheter ablation is clinically indicated for targeting re-entrant ventricular tachycardia (VT) in patients with an implantable cardioverter defibrillator (ICD), but its 1-year VT recurrence rate is high. We hypothesize that 3D wideband LGE is useful for guiding VT ablation.
Goal(s): To determine whether 3D wideband LGE correlates with electroanatomic mapping (EAM) in ICD patients.
Approach: To develop a 3D isotropic wideband LGE pulse sequence and validate it against EAM in ICD patients.
Results: While myocardial scars and gray-zones in LGE correlated with the low voltage areas (<1.5 mV) in EAM, mid-myocardial non-ischemic scars was not correlated between LGE and EAM.
Impact: High-resolution 3D isotropic wideband LGE has potential to increase the success rate of catheter ablation for re-entrant ventricular tachycardia in patients with an implantable cardioverter defibrillation, as well as decrease the procedural time by providing a roadmap prior to ablation.
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