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Abstract #1210

Enhanced motion artifact simulator for structural MRI with MP-RAGE sequence

Tianqi Wu1, Magdalena Sokolska2, David L. Thomas3, Matthew Grech-Sollars1, and Hui Zhang1
1Centre for Medical Image Computing & Department of Computer Science, University College London, London, United Kingdom, 2Medical Physics and Biomedical Engineering, University College London Hospitals, London, United Kingdom, 3Department of Brain Repair and Rehabilitation, UCL Queen Square Institute of Neurology, University College London, London, United Kingdom

Synopsis

Keywords: Analysis/Processing, Simulations, Motion artifacts

Motivation: Motion compromises the utility of structural MRI with MP-RAGE sequence, a workhorse of quantitative neuroimaging research. Recent interest in deep learning-based mitigating solutions, and the scarcity of motion-corrupted data, motivates the need for realistic data simulation. Unfortunately, existing open-source simulators fail to consider important features in real-world acquisitions, including variations in phase-encoding direction, multi-coil acquisition and GRAPPA parallel imaging, resulting in less realistic simulations.

Goal(s): We aim to develop a more realistic motion artifact simulator for MP-RAGE structural MRI.

Approach: We extend TorchIO, an existing simulation framework, to support aforementioned features.

Results: The comparison between simulations demonstrated the importance of including these features.

Impact: The proposed simulation framework can be used to generate more realistic motion-corrupted MRI data from clean images. These data can be served as training sets for deep learning algorithms in motion artifact related applications.

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