Abstract #1227

Helmet RF Applicator Enhances Thermal Magnetic Resonance Theranostics of Brain Tumours

Faezeh Rahimi^1,2, Bilguun Nurzed^1,3, Thomas Wilhelm Eigentler^1,4, Andre Kuehne⁵, Eva Oberacker¹, Pirus Ghadjar⁶, Jason M. Millward^1,7, Rolf Schuhmann², and Thoralf Niendorf^1,5,7

¹Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany, ²FG Theoretische Elektrotechnik, Technische Universität Berlin, Berlin, Germany, ³Berliner Hochschule für Technik, Berlin, Germany, ⁴Chair of Medical Engineering, 3Technische Universität Berlin, Berlin, Germany, ⁵MRI.TOOLS GmbH, Berlin, Germany, ⁶Charite’ Universitätsmedizin, Berlin, Germany, ⁷a joint cooperation between the Charité Medical Faculty and the Max-Delbrück Center for Molecular Medicine, Berlin, Germany

Synopsis

Keywords: RF Arrays & Systems, RF Arrays & Systems, Novel soil design, Brain MRI, 7T, Hyperthermia, Thermal MR, Theranostics, Simulations, Experiments

Motivation: Thermal MR adds an interventional dimension to an MRI device. Ultrahigh-field MRI is an excellent fit for ThermalMR since it benefits from multi-channel transmission in the short wavelength regime

Goal(s): This work investigates the MRI and RF heating performance gain of a multi-channel Tx in a helmet array versus an annular array.

Approach: We aim to enhance B₁⁺ uniformity for brain MRI at 7.0T and enhance SAR_10g for brain thermal therapy using perpendicular RF elements.

Results: Our simulations and phantom experiments demonstrate superior mean B₁⁺ coverage and better B₁⁺ uniformity for MRI and enhanced SAR_10g for thermal therapy using the helmet configuration.

Impact: Dome-shaped helmet transmit RF applicators provide a viable alternative for theranostics involving ultrahigh-field MRI and targeted RF-heating for thermal therapy The performance gain of the helmet transmit RF applicator is demonstrated in numerical simulations and in experiments at 7.0 T.

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