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Abstract #1249

Banding insensitive DESPO for T1 and T2 mapping applied to 3D prostate at 3T.

Ronal Coronado1,2, Carlos Castillo-Passi3,4, Cecilia Besa2,5, and Pablo Irarrazaval1,2,6
1Pontificia Universidad Catolica de Chile, Santiago, Chile, 2Millenium Institute for Intelligent Healthcare Engineering, Santiago, Chile, 3Institute for Biological and Medical Engineering, Pontificia Universidad Católica de Chile, Santiago, Chile, 4School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 5Department of Radiology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile, 6Institute for Biological and Medical Engineering, Santiago, Chile

Synopsis

Keywords: Artifacts, Prostate, Banding artifacts, bSSFP mapping

Motivation: DESPO is a robust T2 brain mapping technique based on balanced steady-state free precession (bSSFP). However, it is susceptible to off-resonance artifacts, especially in areas with high susceptibility changes, such as the prostate.

Goal(s): Our proposed method, DESPO+, integrates the complete bSSFP and spoiled-gradient echo (SPGR) models, using a simulation-based approach for 3D T1/T2 maps in the prostate region.

Approach: We employed a simulated-based method of the full bSSFP and SPGR models incluiding off-resonance to reconstruct T1/T2/PD simultaneously.

Results: DESPO+ provides off-resonance insensitive with high-resolution 3D T1/T2 mapping, synthesizing T1-weighted/T2-weighted images using a short scan time of 3.6 minutes, similar to DESPO.

Impact: DESPO+ provides an off-resonance insensitive and customizable solution, enabling high-resolution 3D T1/T2 mapping and synthesized T1-weighted/T2-weighted images for the entire prostate, all achieved within a short scan time of 3.6 minutes, similar to DESPO.m

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Keywords