Keywords: Hybrid & Novel Systems Technology, Hybrid & Novel Systems Technology, Magnetic Particle Imaging, MPI
Motivation: The gold-standard for guiding minimally invasive cardiovascular interventions is X-ray (digital subtraction angiography - DSA). Can we reduce the radiation exposure for clinical staff and patients?
Goal(s): The use of alternative radiation-free imaging methods providing all necessary features can reduce the radiation exposure dramatically.
Approach: The imaging modality Magnetic Particle Imaging (MPI) uses iron-oxide-based nanoparticles as tracer for realtime visualization of dynamic processes. In a first step, this technique could be used to support clinical DSA treatment.
Results: In a first study, a lightweight and portable human-sized MPI scanner has been built and successfully tested under realistic conditions with vascular phantoms within a catheter-lab.
Impact: First simultaneous MPI/DSA hybrid imaging in human-sized phantoms demonstrates the feasibility of scaling-up the MPI technology. With a clinical approved tracer, MPI could be ready for clinical routine.
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