Abstract #1346

Enhanced Leptomeningeal Collateral Visualization in Moyamoya Disease: A 5.0-T 4D NCEMRA Study

Yining Wang¹, Yijun Zhou¹, Shihai Zhao¹, YuXin Yang², Shuo Chen³, Ke Xue², Dong Wang³, Mingli Li¹, Jun Ni⁴, Dong Zhang^5,6,7,8, and Feng Feng¹

¹Department of Radiology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, ²MR Collaboration, United Imaging Research Institute of Intelligent Imaging, Beijing, China, ³United Imaging Research Institute of Intelligent Imaging, Beijing, China, ⁴Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, ⁵Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China, ⁶China National Clinical Research Center for Neurological Diseases, Beijing, China, ⁷Department of Neurosurgery, Beijing Hospital, National Center of Gerontology, Beijing, China, ⁸Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China

Synopsis

Keywords: Blood Vessels, Blood vessels, 5.0-T magnetic resonance angiography

Motivation: Moyamoya disease necessitates precise visualization of cerebral vessels for management, but current imaging may be inadequate.

Goal(s): To ascertain if 5.0-T 4D NCEMRA offers superior imaging of collateral circulation in Moyamoya disease compared to traditional TOF MRA.

Approach: Utilized 5.0-T MRI to compare 4D NCEMRA and TOF MRA in visualizing leptomeningeal collateral anastomoses in 19 patients.

Results: 5.0-T 4D NCEMRA outperformed TOF MRA, particularly in identifying leptomeningeal collaterals, with significant statistical support.

Impact: The study underscores 5.0-T 4D NCEMRA's potential to enhance cerebral vascular mapping in Moyamoya disease, prompting advancements in diagnostic and therapeutic strategies, possibly leading to more personalized patient care.

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