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Abstract #1374

Using water beads as static tissue in a Circle of Willis flow phantom in 4D flow MRI

Ali El Ahmar1, Patrick Winter1,2, Stephan König1, Adrian Duckert1, Marie-Luise Kromrey3, and Susanne Schnell1,2
1Department of Medical Physics, University of Greifswald, Greifswald, Germany, 2Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States, 3Institute of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, Germany

Synopsis

Keywords: Blood Vessels, Blood vessels

Motivation: While previous research has focused on realistic vessel and flow replication, the background tissue mimicking in 4D flow MRI remains unexplored despite its significant impact on phase correction accuracy.

Goal(s): Aims to identify a suitable material for a Circle of Willis flow phantom that can mimic background static tissue, ensure transparency, and constrain vessel motion.

Approach: Transparent water beads soaked in a Gd-doped solution were used as background static tissue in a flow phantom. A MATLAB tool was used for the post-processing of the 4D-flow data.

Results: Water beads effectively minimized motion artifacts, and increased the number of time-averaged streamlines and their quality.

Impact: This study introduces a practical solution, to enhance the accuracy of in-vitro 4D Flow MRI of complex vessel phantoms by mitigating motion artifacts. The transparent water beads offer a cost-effective and easily exchangeable alternative for mimicking background static tissue.

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