Abstract #1392

Association of duration of dialysis and myocardial damage in end-stage renal disease patients: assessed by cardiovascular magnetic resonance

Zhiyue Wang¹, Haodong Guo², Fei Liu², Xiaoping Wang², Haige Li², and Weiyin Vivian Liu³

¹Radiology, the Second Affiliated Hospital of Nanjing Medical University, Nanjing, China, ²the Second Affiliated Hospital of Nanjing Medical University, Nanjing, China, ³GE Healthcare, MR Research China, Beijing, China

Synopsis

Keywords: Myocardium, Cardiovascular

Motivation: Explore relationship between cardiac image and duration of dialysis.

Goal(s): To evaluate myocardial damage using CMR in end-stage renal disease (ESRD) patients undergoing hemodialysis and further explore its relationship with duration of dialysis.

Approach: Patients with long- and short-term dialysis were included. CMR parameters (native T1 value and ECV) and two biochemical results (brain pro-natriuretic peptide and troponin T) were compared.

Results: Native T1 value, ECV, brain pro-natriuretic peptide and troponin T were significant different in two groups. Multiple linear regression analysis showed that native T1 value and ECV were independently associated with duration of dialysis and troponin T.

Impact: Quantification of myocardial fibrosis in ESRD is challenging. CMR imaging is useful in the detection of cardiac damage. Longer durations of dialysis may lead to poor outcomes. Our purpose was to explore relationship between cardiac image and duration of dialysis.

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