Keywords: fMRI Analysis, Breast, Cancer
Motivation: APTWI and DWI had still some controversies between their parameters and some biological status.
Goal(s): To assess the value of amide proton transfer-weighted imaging (APTWI) and diffusion weighted imaging (DWI) in differentiating biological subtypes and predicting the biological status of breast tumors.
Approach: The Kruskal-Wallis H test and Post-hoc pairwise comparison, Pearson's correlation analysis. Independent samples t-test. Receiver operating characteristic (ROC) analysis.
Results: MTRasym (3.5 ppm) was higher in breast tumours that were TN, ER-, PR-, and high-Ki-67. Compared to DWI, APTWI is more useful in predicting the biological status of breast cancers.
Impact: Compared to DWI, APTWI is more useful in predicting the biological status of breast cancers.
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