Abstract #1502

Non-Contrast Myocardium Perfusion using Stacks-of-Stars (SoS) Time-SLIP

Diana Vucevic¹, Vadim Malis¹, Paul Kim², and Mitsue Miyazaki¹

¹Radiology, University of California San Diego, San Diego, CA, United States, ²Cardiology, University of California San Diego, San Diego, CA, United States

Synopsis

Keywords: Myocardium, Cardiovascular

Motivation: Coronary Arterial Disease (CAD) evaluations often require myocardium perfusion exams. Many CAD patients also have stents which makes difficult to evaluate images due to susceptibility artifacts. A reliable non-contrast MR perfusion technique in CAD patients with stents is needed.

Goal(s): To introduce Time-SLIP technique with Stack-of-Stars (SoS) sequence for more inclusive myocardial assessments without the need for contrast mediums.

Approach: Implemented diaphragm navigator echoes and T2-prep with the SoS sequence, refined through phantom trials, for tagging the proximal aortic root blood flow to visualize myocardial perfusion.

Results: Preliminary in-vivo scans indicate reduced stent-related artifacts and the feasibility of non-contrast perfusion quantification.

Impact: Our non-contrast myocardial perfusion approach offers a safer CAD evaluation, reducing risks from contrast agents. This method opens doors for inclusive patient assessments and encourages further refinement in non-invasive cardiac diagnostics.

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