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Abstract #1504

Rapid 2D Myocardial Late Gadolinium Enhancement Imaging with Resolution Enhancement Generative Adversarial Inline Neural Network

Omer Burak Demirel1, Tess Wallace1,2, Patrick Pierce1, Scott Johnson1, Salah Assana1, Jennifer Rodriguez1, Kathryn Arcand1, Kelvin Chow3, Warren J Manning1,4, and Reza Nezafat1
1Department of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States, 2Siemens Medical Solutions USA, Boston, MA, United States, 3Cardiovascular MR R&D, Siemens Healthcare Ltd., Calgary, AB, Canada, 4Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, United States

Synopsis

Keywords: Myocardium, Cardiovascular

Motivation: 2D high-resolution late gadolinium enhancement (LGE) imaging can benefit from shorter scan times. Current acceleration techniques lead large signal-to-noise (SNR) penalties, reducing diagnostic quality while longer breath-holds increases scan time and makes the imaging susceptible to artifacts.

Goal(s): To assess the feasibility of a rapid 2D LGE imaging using Resolution Enhancement Generative Adversarial Inline Neural Network (REGAIN).

Approach: Images were acquired with 3.3 and 5.7-fold accelerations, reconstructed using REGAIN, and compared with 1.8-fold GRAPPA acceleration.

Results: REGAIN successfully improved visual image sharpness in LGE images acquired with 3.3-fold (~6-second) and 5.7-fold (~10-second) accelerations. Image quality was comparable to 1.8-fold (~16-second) GRAPPA acceleration.

Impact: REGAIN enables accelerated LGE imaging with significantly reduced breath-hold duration.

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