Keywords: Vascular, DSC & DCE Perfusion
Motivation: By investigating changes in bone marrow microvascular permeability and bone microstructure, we can explore the key pathological and physiological mechanisms underlying impaired vascular repair in diabetes
Goal(s): To assess the functional changes in endothelial progenitor cells (EPCs) and alterations in bone microstructure in rabbits with severe limb ischemia complicated by diabetes mellitus using DCE-MRI and micro Micro-CT
Approach: 30 healthy male New Zealand white rabbits underwent sagittal MR imaging of the femoral bone proximal coronal plane at fixed time points
Results: DCE-MRI combined with Micro-CT quantitative parameters is feasible to evaluate endothelial progenitor cell function and changes in bone microstructure in diabetes mellitus
Impact: The results of this study will provide a new perspective on the pathological and physiological mechanisms underlying bone marrow changes in diabetic patients with concurrent critical limb ischemia.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords