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Abstract #1538

Quantitative MRI Evaluation of the Supraspinatus-Deltoid Muscle Force Couple with T2* Mapping

Erin C Argentieri1, Peder E.Z Larson1, Drew A. Lansdown2, Brian T. Feeley2, Sharmila Majumdar1, and Misung Han1
1Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States, 2Department of Orthopaedic Surgery, University of California San Francisco, San Francisco, CA, United States

Synopsis

Keywords: Muscle, MSK, UTE, T2* mapping, shoulder, muscle, supraspinatus, deltoid

Motivation: No previous studies have evaluated relative supraspinatus-deltoid force couple (Supra-Delt-FC) muscle T2*-metrics or considered their potential as biomarkers for Supra-Delt-FC function

Goal(s): Evaluate/compare Supra-Delt-FC T2*-values within 6 supraspinatus injured-case, and 6 (age/sex matched) uninjured-control subjects

Approach: Unilateral, 3T, 3D-Cones, 15-echo-UTE MRI acquisitions were utilized for calculation and evaluation of Supra-Delt-FC muscle T2*-values

Results: Independent evaluations of deltoid and supraspinatus muscle T2*-values revealed no significant differences between injured-case and uninjured-control subjects. However, evaluation of relative T2*-metrics (mean difference & FC-ratios) revealed significant case-to-control differences – suggesting that relative supraspinatus-to-deltoid T2* metrics may be more sensitive to alterations in Supra-Delt-FC and shoulder function following injury

Impact: While independent comparisons of respective supraspinatus and deltoid muscle T2*-values revealed no significant case-to-control differences, relative Supra-Delt-FC muscle T2*-metrics were significantly different between groups. Results suggest that relative Supra-Delt-FC muscle T2*-metrics may be more sensitive to alterations in Supra-Delt-FC function.

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Keywords