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Abstract #1652

Preoperative Left Atrial Strain Predicts Outcome in Patients with Hypertrophic Obstructive Cardiomyopathy after Myectomy

Shujuan Yang1 and Shihua Zhao1
1Fuwai Hospital, Beijing, China

Synopsis

Keywords: Myocardium, Cardiovascular

Motivation: The association of preoperative LA strain assessed by cardiac magnetic resonance (CMR)-FT with the late outcome of HOCM patients after myectomy remains unknown.

Goal(s): To evaluate the prognostic value of preoperative LA strain in HOCM following myectomy.

Approach: In this retrospective, single-center study, 802 adult patients with HOCM after myectomy were included, who underwent preoperative CMR with clinical outcome follow-up.

Results: LA reservoir strain ≤ 22.9% was independently associated with postoperative adverse outcomes. Incorporating LA reservoir strain, the performance of the HCM Risk-SCD score improved for SCD prediction (C-statistic: from 0.62 to 0.69; log-likelihood: from -110.31 to -108.27, P=.04).

Impact: HOCM patients with reduced preoperative LA reservoir strain tend to have poor postoperative outcomes, so reinforced follow-ups may be required in those patients.

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