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Abstract #1660

Effects of blood uric acid levels and omega-6/omega-3 on left heart function: a CMR feature tracking analysis

Jianbo Lyu1, Zhang Chen2, Miaomiao Bai1, and Xiaofeng Qu1
1The Second Affiliated Hospital of Dalian Medical University, Dalian, China, 2MR Research Collaboration, Siemens Healthineers, Beijing, China

Synopsis

Keywords: Myocardium, Cardiovascular

Motivation: Hyperuricemia and abnormal ω-6/ω-3 values contribute to cardiac damage, but the specific mechanisms remain unclear.

Goal(s): To explore the effects of uric acid and ω-6/ω-3 values on left heart function using cardiac magnetic resonance feature tracking.

Approach: We utilized the TrueFISP cine sequence, CVI42 software, and univariate and multivariate linear regression analyses to identify relationships of uric acid and ω-6/ω-3 values with left heart function.

Results: High ω6/ω3 values may exacerbate left ventricular dysfunction in patients with hyperuricemia.

Impact: Our findings concerning the effects of uric acid and ω-6/ω-3 values on left heart function will help to improve the clinical management and treatment of patients with hyperuricemia.

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