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Abstract #1678

Ventricular stroke volume is linked with thalamic volume in normal adult brains

Chia-Ying Liu1, Chikara Noda2, Bharath Ambale-Venkatesh2, Yoko Kato2, Yoshimori Kassai3, David A Bluemke4, and Joao A.C Lima2
1Canon Medical Systems Corporation, Ellicott City, MD, United States, 2Johns Hopkins University, Baltimore, MD, United States, 3Canon Medical Systems Corporation, Tochigi, Japan, 4University of Wisconsin, Madison, WI, United States

Synopsis

Keywords: Myocardium, Brain, cardiac function

Motivation: Impaired cardiac function has been associated with cognitive deterioration. However, the correlation of cardiovascular function to cerebral structures remains unclear.

Goal(s): We studied whether the ventricular function is associated with measures of subcortical volumes in a general patient population.

Approach: All participants were imaged using a 3T MRI systems. Cardiac 2D SSFP CINE was acquired for cardiac function. Brain structural images were acquired using a 3D MPRAGE.

Results: Among seven subcortical structures examined in 101 healthy adults, only the thalamic volume demonstrated a positive association with left ventricular stroke volume and right ventricular end diastolic volume.

Impact: In healthy adults, the thalamic volume demonstrated a positive association with left and right ventricular stroke volume.

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Keywords