Keywords: Psychiatric Disorders, Brain, Post-traumatic Stress Disorder
Motivation: Neurochemical alterations in PTSD are well-researched across various brain regions, yet understanding their connection to symptoms remains unexplored.
Goal(s): Our aim was to determine the association between the neurochemical profile and emotional/cognitive symptoms in diagnosed PTSD individuals and healthy controls.
Approach: Participants underwent an MRS scan and CNS Vital Signs survey. Correlations between metabolites and survey scores were examined.
Results: We found significant differences across several PTSD symptoms, for which the severity correlated with metabolite levels alterations in the ACC and hippocampus.
Impact: By understanding correlation between neurochemical alternations and clinical symptom severity, this study provides valuable insights into the pathways of PTSD. It paves the way for innovative approaches in managing neurological disorders.
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