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Abstract #1772

Quantitative MRI with Automated Histogram Analysis Based on Self-Supervised Learning of Organ Segmentation: Demonstration for Liver T1 Mapping

Lavanya Umapathy1,2, Prerna Luthra1,3, Jingjia Chen1,2, Daniel Sodickson1,2, and Li Feng1,2
1Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States, 2Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States, 3Department of Electrical and Computer Engineering, NYU Tandon School of Engineering, New York, NY, United States

Synopsis

Keywords: Analysis/Processing, Liver, Machine learning, quantitative imaging

Motivation: Extensive recent work has been devoted to quantitative MRI, but practical implementation of quantitative parameter mapping is hindered by the lack of tools for easy visualization and automated analysis.

Goal(s): We demonstrate the applicability of a self-supervised contrastive pretraining framework for organ segmentation in automated analysis of free-breathing 3D liver T1 mapping.

Approach: A DL model is pretrained to learn T1 contrast information from multi-contrast images acquired for T1 parameter mapping.

Results: With few labeled examples, an organ segmentation framework was developed, and its utility in interpreting parameter maps was demonstrated.

Impact: Multi-contrast information from images typically acquired for parameter estimation in quantitative MRI can be leveraged to pretrain organ segmentation models with self-supervision, enabling automated analysis of quantitative parameter maps.

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Keywords