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Abstract #1816

Accelerated and Accurate Myocardial Multi-Parametric Quantitative Mapping using Bloch Equation Simulation-based Fitting

Yiming Tao1, Wenjian Liu1, Zhenfeng Lv1, Haikun Qi1,2, and Peng Hu1,2
1School of Biomedical Engineering, ShanghaiTech University, Shanghai, China, 2Shanghai Clinical Research and Trial Center, ShanghaiTech University, Shanghai, China

Synopsis

Keywords: Myocardium, Quantitative Imaging

Motivation: Motivated by the time-consuming process of dictionary matching in quantitative cardiac MRI, this study aims to develop a faster and more accurate method for myocardial multi-parametric quantitative mapping.

Goal(s): The goal is to overcome the limitations of discretization errors and incomplete inversion pulses, which lead to inaccurate parameter estimation.

Approach: The proposed approach utilizes Bloch equation simulation-based fitting, enabling rapid reconstruction of T1, T2, and T1ρ maps simultaneously.

Results: Experimental results demonstrate excellent quality of fit and significant acceleration (100x) compared to the traditional method.

Impact: This novel method has the potential to revolutionize myocardial quantitative mapping, offering improved efficiency and precision in clinical applications.

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