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Abstract #1837

Quality Assessment Tool using Deep Learning for GABA-Edited MRS data

Hanna Bugler1,2,3,4, Roberto Souza3,5, and Ashley D. Harris2,3,4
1Department of Biomedical Engineering, University of Calgary, Calgary, AB, Canada, 2Department of Radiology, University of Calgary, Calgary, AB, Canada, 3Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada, 4Alberta Children's Hospital Research Institute, University of Calgary, Calgary, AB, Canada, 5Department of Electrical & Software Engineering, University of Calgary, Calgary, AB, Canada

Synopsis

Keywords: Spectroscopy, Spectroscopy, Machine Learning/Artificial Intelligence, Artifacts, Data Processing, Software Tools, Simulations, Brain, Pediatric

Motivation: GABA-edited MRS suffers from data quality challenges due to its low signal to noise ratio (SNR).

Goal(s): We propose an automated labeling algorithm for transient quality and a dual-domain deep learning model for filtering spectra transients based on quality.

Approach: We trained our model with simulated data containing commonly occurring artifacts labelled with our continuous automated labelling algorithm which ranges from –1 (poor quality) to +1 (good quality). We subsequently evaluated our model’s performance by removing (filtering) poor quality transients corresponding to quality values less than 0.

Results: Our model outperformed qualitatively simple averaging using all collected transients for 70-80% of scans.

Impact: Our model can successfully assign a continuous quality score between –1 (poor) and +1 (good) to GABA-edited MRS difference data (i.e., a single ON-OFF edit pair) which when used for filtering, improves MRS quality metrics compared to simple transient averaging.

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Keywords