Keywords: Spectroscopy, Spectroscopy
Motivation: Nuisance signal contamination and challenges associated with implementation involving advanced RF pulses and sequence hinder clinical adoption. Simplified sequence implementation and dissemination are crucial for community-driven advancement and vendor support.
Goal(s): Our goal is to integrate CHEmical-shift selective Adiabatic refocusing Pulses(CHEAP) on the Philips platform via Pulseq open-source platform, creating advanced MRSI sequences that refine metabolite analysis by minimizing unwanted signals.
Approach: Integrating chemically selective adiabatic 2𝜋-refocus pulses in Pulseq achieved optimal spectrum coverage, reducing interference from residual water and lipid signals.
Results: Implementing the CHEAP sequence significantly mitigated interference from residual water and lipid signals, demonstrating its potential for advancing MRSI.
Impact: The implementation of CHEAP sequence via Pulseq promises a standardized, shareable method, fostering collaboration and enabling precise metabolic studies. This advancement in MRS techniques may significantly improve reproducibility across sites and enhance capacity for metabolic profiling in health and disease.
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