Keywords: Image Reconstruction, Perfusion, Dynamic Contrast Enhancement, Real-Time MRI
Motivation: Dynamic contrast-enhanced (DCE) MRI requires both high spatial and high temporal resolution for accurate quantification and delineation. In practice, temporal resolution is often traded for spatial resolution and volume coverage.
Goal(s): To develop a reconstruction method that offers both high spatial and temporal resolution.
Approach: We describe a two-stage reconstruction technique that consistently produces high-temporal, high-spatial resolution estimates of the ground truth data and is more accurate than current state-of-the-art methods.
Results: The proposed method achieves high quality reconstruction with as few as one acquired spoke per frame when radial sampling is used.
Impact: The theoretical and practical success of the spatial subspace method over temporal subspace methods encourages further research on the topic. Furthermore, reconstruction at 1 spoke per frame enables larger imaging volumes, thus more capable imaging tools.
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