Abstract #1885

Myelin-sensitive inversion recovery (MySIR) for quantification of myelin in the peripheral nerve

Takayuki Sada¹, Hajime Yokota², Keisuke Nitta¹, Ryuna Kurosawa¹, Hirotaka Sato¹, Koji Matsumoto¹, Takashi Namiki³, Masami Yoneyama³, Guillaume Gilbert⁴, Yoshitada Masuda¹, and Takashi Uno²

¹Department of Radiology, Chiba University Hospital, Chiba, Japan, ²Diagnostic Radiology and Radiation Oncology, Graduate School of Medicine, Chiba University, Chiba, Japan, ³Philips Japan, Tokyo, Japan, ⁴Philips Canada, Mississauga, ON, Canada

Synopsis

Keywords: Peripheral Nerves, Neurography

Motivation: Quantification of myelin in peripheral nerves remains challenging.

Goal(s): To evaluate new imaging techniques that quantify myelin in the peripheral nerve.

Approach: Myelin-sensitive inversion recovery (MySIR) was compared with inhomogeneous magnetization transfer (ihMT) for its ability to reflect myelin value and spatial resolution in the peripheral nerve.

Results: Myelin values of MySIR and ihMT were strongly correlated. MySIR had a better ability to visualize nerve fascicles than ihMT.

Impact: MySIR could quantify myelin while maintaining high spacial resolution in peripheral nerves.

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