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Abstract #1890

Feasibility of 3D Reduced-FOV Multi-shot Isotropic DWI in Optic Nerves

Chenglang Yuan1, Shihui Chen1, Liyuan Liang1,2, Xiaorui Xu3, Hailin Xiong1, Yi Li1, Tianbaige Liu1, and Hing-Chiu Chang1,2
1Department of Biomedical Engineering, The Chinese University of Hong Kong, Hong Kong, China, 2Multi-Scale Medical Robotics Center, Hong Kong, China, 3Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong, China

Synopsis

Keywords: Head & Neck/ENT, Nerves, multi-shot, reduced-FOV, 3D isotropic DWI, optic nerves

Motivation: Conventional 2D DWI sequences suffer from several disadvantages, therefore hindering the clinical visual assessment of optic nerves.

Goal(s): This study aims to enable a 3D reduced-FOV multi-shot isotropic DWI sequence for optic nerves DWI and verify its feasibility.

Approach: The pulse sequence and corresponding reconstruction algorithm of 3D reduced-FOV 2-shot isotropic DWI was developed to achieve effective and accurate reconstruction of optic nerves.

Results: Preliminary results have shown the feasibility of our method in depicting the optic nerves with high resolution and high fidelity, therefore potentially benefiting the clinical applications of optic nerves DWI.

Impact: 3D reduced-FOV multi-shot isotropic optic nerves DWI shows superior advantages of high resolution and high fidelity compared with other conventional DWI sequences, which should be further investigated and applied for clinical applications of optic nerves.

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Keywords