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Abstract #1965

Denoising AutoEncoder as a Pre-processor for Knee MRI Analysis

Shengjia Chen1,2, Ozkan Cigdem1,2, Chaojie Zhang1,2, Haresh Rengaraj Rajamohan3, Kyunghyun Cho3, Richard Kijowski2, and Cem M. Deniz1,2
1Center for Advanced Imaging Innovation and Research (CAI2R), Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States, 2Bernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, NY, United States, 3Center for Data Science, New York University, New York, NY, United States

Synopsis

Keywords: Analysis/Processing, Data Processing

Motivation: Pre-processing MR images is a necessary step prior to image analysis due to variability of intensity scale in MR images.

Goal(s): To develop a deep learning algorithm for standardizing knee MR images prior to analysis.

Approach: We developed a denoising autoencoder with VNet architecture achieving on-the-fly image pre-processing (Bias field correction and intensity normalization) and denoising. Image quality was evaluated using SNR, NMSE, PSNR, and SSIM.

Results: Our approach achieved an improved SNR with an efficient runtime compared to conventional pre-processing methods.

Impact: Our DL-based knee MRI pre-processing tool generates standardized MRI outputs for image analysis and DL model development. This tool can be incorporated into a wide range of image analysis pipelines for the knee.

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Keywords