Keywords: Arterial Spin Labelling, Arterial spin labelling
Motivation: We have recently shown that a PCASL-bSSFP sequence provides high quality perfusion images of the lung. However, the perfusion signal is dependent on the respective cardiac cycle.
Goal(s): Our aim was to further increase the perfusion signal of the lung parenchyma and/or to shorten the examination time using a new PCASL approach with multiple labeling.
Approach: Four volunteers were examined using an ECG-triggered multiple labeling PCASL-bSSFP sequence with different number of labeling pulses, post labeling delays and repetition delays.
Results: The PCASL sequence with multiple labeling appears to provide a higher perfusion signal of the lung parenchyma, reducing sensitivity to cardiac cycle variations.
Impact: The new PCASL approach with multiple labeling appears to provide a significantly higher perfusion signal of the lung than measurements with single labeling pulse. The sequence makes the PCASL technique more robust and faster for future application in clinical practice.
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