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Abstract #2002

Renal multiple post label times arterial spin label (ASL) read out by turbo spin echo (TSE)

Yizhe Zhang1,2,3, Quan Tao2,3,4, Zelong Chen5, Zhigang Wu6, Wenyan Zhang1,2,3, Qianqian Zhang1,2,3, Kan Deng7, Peng Wu8, Yikai Xu5, and Yanqiu Feng1,2,3,4
1School of Biomedical Engineering, Southern Medical University, Guangzhou, China, 2Guangdong Provincial Key Laboratory of Medical Image Processing, Southern Medical University, Guangzhou, China, 3Guangdong Provincial Engineering Laboratory for Medical Imaging and Diagnostic Technology, Southern Medical University, Guangzhou, China, 4Department of Rehabilitation, Zhujiang Hospital, Southern Medical University, Guangzhou, China, 5Medical Imaging Center, Nanfang Hospital, Southern Medical University, Guangzhou, China, 6Philips Healthcare, Shenzhen, China, 7Philips Healthcare, Guangzhou, China, 8Philips Healthcare, Shanghai, China

Synopsis

Keywords: Arterial Spin Labelling, Arterial spin labelling

Motivation: Renal imaging using echo planar imaging (EPI) readout may be sensitive to field inhomogeneities and induced ghost artifact. Besides, single inversion time is not enough for renal blood flow (RBF) quantification. Investigation of more stable clinical arterial spin label (ASL) imaging methods is required.

Goal(s): We aimed to design a stable clinical ASL sequence to quantify RBF accurately.

Approach: Multiple inversion time (TIs) readout by turbo spin echo (TSE) was processed, and the repeatability of quantification was evaluated in volunteers (n=7).

Results: Multiple TIs combined with TSE readout of FAIR-ASL provided more accurate RBF measurement and highly repeatability compare with pcASL-EPI.

Impact: Multi-PLDs readout by TSE may provide a stable clinical ASL-FAIR sequences to accurately quantify RBF.

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