Abstract #2008

Quantitative measurement of renal arterial spin labeling: a noninvasive indicator of perfusion in renal artery stenosis

Xiaoxiao Zhang¹, Gumuyang Zhang², Lili Xu², Jiahui Zhang², Xin Bai², Li Chen², Qianyu Peng², Erjia Guo², Jinxia Zhu³, Bernd Kuehn⁴, Zhengyu Jin², and Hao Sun²

¹Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China, ²Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, ³MR Research Collaboration, Siemens Healthineers Ltd., Beijing, China, ⁴MR Application Predevelopment, Siemens Healthcare GmbH, Beijing, China

Synopsis

Keywords: Arterial Spin Labelling, Perfusion

Motivation: There are few validated noninvasive indicators for renal perfusion and renal function in patients with renal artery stenosis (RAS)

Goal(s): To explore the utility of arterial spin labeling (ASL) as a noninvasive indicator of renal perfusion and function in patients with RAS.

Approach: We evaluated correlations between ASL-measured preoperative renal blood flow (RBF) and renal function, then compared preoperative and postoperative RBF.

Results: ASL-measured RBF was significantly correlated with renal function. ASL was able to evaluate perfusion improvement in patients with RAS after interventional therapy.

Impact: ASL can be used as an indicator of renal function and perfusion in patients with RAS. It can also be used to assess changes in renal perfusion after interventional therapy.

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