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Abstract #2020

Improving the Robustness of Pseudo-Continuous Arterial Spin Labeling in the Intraoperative MRI Setting.

Carmen Sánchez-Albardíaz1, Marta Calvo-Imirizaldu1, Verónica Aramendía-Vidaurreta1, Marta Vidorreta2, Bartolomé Bejarano3, Lain H Gonzalez-Quarante3, Ana Aransay García3, Cristina Honorato4, Elena Cacho-Asenjo4, Antonio Martinez-Simon4, and María A Fernández-Seara1
1Radiology, Clínica Universidad de Navarra, Pamplona, Spain, 2Siemens Healthcare, Madrid, Spain, 3Neurosurgery, Clínica Universidad de Navarra, Pamplona, Spain, 4Anesthesia, Perioperative Medicine and Critical Care, Clínica Universidad de Navarra, Pamplona, Spain

Synopsis

Keywords: Arterial Spin Labelling, Arterial spin labelling

Motivation: Improvement of the intraoperative pseudo-continuous arterial spin labeling images for resection control in brain tumor surgery at 3T.

Goal(s): Evaluate the effect of shortening RF pulse duration and gap on the labeling efficiency of PCASL and to test it in the intraoperative setting.

Approach: A study in 10 healthy volunteers was done approximating the off-resonance effects at the labeling plane. 2 PCASL sequences were tested in 2 patients.

Results: A PCASL sequence robust to off-resonance effects is obtained by shortening RF duration and gap.

Impact: Shortening the RF duration and gap improves the PCASL labeling efficiency at high B0 off-resonance values at the labeling plane.

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Keywords