Keywords: Tractography, Surgery
Motivation: Intraoperative fiber tractography could help to elucidate the nature of cerebellar mutism syndrome after tumor resection in pediatric posterior fossa tumor (pPFT) patients.
Goal(s): To explore the feasibility of reconstructing eloquent fiber tracts with a short intraoperative diffusion MRI scan in pPFT patients.
Approach: We reconstructed tracts intraoperatively in four pPFT patients and compared their structural properties to preoperative scans obtained with the same settings.
Results: It is in general possible, but challenging, to reconstruct the eloquent tracts in pre- and intraoperative data of pPFT patients. However, further optimization of the fiber tractography model is required to increase their quality.
Impact: The impact of the mechanical manipulation of the surgical procedure on the eloquent pathways in pediatric posterior fossa tumor patients is investigated through the development of a reliable fiber tractography model for intraoperative diffusion MRI.
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