Meeting Banner
Abstract #2176

Improved chemical exchange detection using magnetization transfer (MT) effect independent composite metric (R2-R1rho): a preliminary study

Yurui Qian1, Ziqin Zhou1,2, Jian Hou1, Ziqiang Yu1, Baiyan Jiang1,3, and Weitian Chen1
1Imaging and Interventional Radiology, The Chinese University of Hong Kong, Hong Kong, Hong Kong, 2MR Collaboration, Siemens Healthineers Ltd, Hong Kong, Hong Kong, 3Illuminatio Medical Technology Limited, Hong Kong, Hong Kong

Synopsis

Keywords: Relaxometry, Contrast Mechanisms, Spin Lock

Motivation: Composite metric R2-R1rho (1/T2–1/T1rho) could be utilized for probing chemical exchange.. However, a persistent challenge lies in the confounding influences of magnetization transfer (MT) effects on R2, which was not fully discussed in literatures.

Goal(s): In this study, we reported our investigation on this effect and proposed an acquisition strategy to improve the specificity of the composite metric (R2-R1rho) to thethe chemical exchange effect.

Approach: We demonstrated our findings and the proposed method using simulation, phantom, and in vivo experiments.

Results: From our preliminary results, composite metric (R2-R1rho) to detect chemical exchange without the influence from magnetization transfer effect.

Impact: Using improved composite metric (R2-R1rho) to detect chemical exchange without the influence from magnetization transfer effect.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords