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Abstract #2247

MR-to-CT Synthesis in MR-only Radiotherapy Based on Deep Learning

Yibo Hu1, Shi'ang Zhang1, Wentao Li2, Jianqi Sun1, and Lisa X. Xu1
1Shanghai Jiao Tong University, Shanghai, China, 2Fudan University Shanghai Cancer Center, Shanghai, China

Synopsis

Keywords: Analysis/Processing, Liver, MR radiotherapy, medical image synthesis,

Motivation: MRI-only radiotherapy requires synthesizing MR images into CT-equivalent images to calculate the radiation dose. However, the current synthesis methods are limited when applied to small anatomical regions, such as tumors.

Goal(s): Our goal was to develop a novel MR-to-CT synthesis algorithm that produces better results for small anatomical structures.

Approach: We introduced a multi-branch hybrid perceptual generative model incorporating an attention mechanism to synthesize different scales anatomical structures.

Results: Our proposed algorithms yield favorable results for small anatomical structures based on physician feedback and quantitative assessments.


Impact: The proposed synthesis algorithm simplifies and speeds up MRI-only radiotherapy workflow. It is also applicable to other fields of medical image synthesis, such as multi-modal image diagnosis treatment.

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