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Abstract #2280

Non-Contrast MR Perfusion Imaging of the Hip

Mitsue Miyazaki1, Diana Vucevic1, Vadim Malis1, Anya Mesa1, and Won C Bae1,2
1University of California, San Diego, La Jolla, CA, United States, 2VA San Diego Healthcare System, San Diego, CA, United States

Synopsis

Keywords: Bone, Perfusion, Hip, avascular necrosis, blood flow

Motivation: Avascular necrosis of the hip is due to disturbed blood supply related to various causes. Early evaluation currently requires contrast enhanced MR perfusion imaging.

Goal(s): Evaluate human hip perfusion using non-contrast MR perfusion technique.

Approach: Bilateral hips of healthy volunteers were imaged coronally at 3-T using a 2D spin labeling MR perfusion technique using tag-on tag-off acquisition at varying TI and processing to determine tagged blood signal into the acetabulum, femoral head, and femoral neck.

Results: We found distinct perfusion signal in the acetabulum but the signal in the femoral head and neck were more subdued.

Impact: This study demonstrates the feasibility of non-contrast MR perfusion imaging of the human hip, with future application in evaluation of avascular necrosis.

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Keywords