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Abstract #2311

Microstructural Alterations in Language-Related White Matter Tracts in Post Basal Ganglia Stroke: A DSI study

Xuewei Li1, Hongwei Zhou1, and Yueluan Jiang2
1The First Hospital of Jilin University, Changchun, China, 2MR Research Collaboration, Siemens Healthineers, Beijing, China

Synopsis

Keywords: Stroke, Diffusion/other diffusion imaging techniques

Motivation: Post-stroke basal ganglia aphasia is common in clinical practice, and it is necessary to explain the causes of aphasia after basal ganglia infarction from imaging perspectives.

Goal(s): To obtain white matter fiber bundles associated with the occurrence of basal ganglia aphasia.

Approach: To apply DSI studio and use deterministic fiber-tracking algorithm to reconstruct language-related fiber bundles and measurequantitative anisotropy (QA) of each white matter tracts.

Results: The damage to language related white matter fiber bundles such as corpus callosum fibers may be related to the occurrence of basal ganglia aphasia after stroke.

Impact: By studying the integrity of white matter fiber bundles of basal ganglia aphasia after stroke, it provides an auxiliary role for clinical analysis of its pathogenesis.

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Keywords