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Abstract #2334

Feasibility of Multiplexed Sensitivity-Encoding diffusion tensor imaging (MUSE-DTI) in cervical spondylotic myelopathy

Haoyue Shao1, Xiangyu Tang1, Weiyin Liu2, and Qiufeng Liu1
1Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China, 2GE HealthCare, Beijing, China

Synopsis

Keywords: Spinal Cord, Neuro, cervical spondylotic myelopathy

Motivation: MUSE-DTI may elevate spatial resolution and image quality in cervical spine.

Goal(s): This study aimed to investigate the clinical diagnosis value of MUSE-DTI in patients with cervical spondylotic myelopathy (CSM).

Approach: Independent T-test or Mann-Whitney t test and Spearman correlation analysis was used to investigate the differences of FA and ADC values between each two different stages and the correlation to JOA scores.

Results: All MUSE-DTI derived values at MCL were correlated with the clinical JOA scores. The axial diffusivity (AD) values were most sensitive to the secondary damage of distal spinal cord.

Impact: This study presented the ability of MUSE-DTI in better display cervical spinal cord and spinal cord injury with more reliable measurements for the clinical diagnosis and treatment of CSM patients.

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