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Abstract #2342

Spinal cord atrophy in aging and across different neurological diseases

Xiaoqin Zhu1, Yunyun Duan1, Zhizheng Zhuo1, Min Guo1, Xianchang Zhang2, and Yaou Liu1
1Deaprtment of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China, 2MR Research Collaboration, Siemens Healthineers Ltd., Beijing, China

Synopsis

Keywords: Spinal Cord, Spinal Cord

Motivation: Determining the clinical significance of spinal cord changes across various neurological diseases.

Goal(s): Determining the clinical significance of spinal cord changes across various neurological diseases.

Approach: We compared the spinal cord changes across various neurological diseases, followed by analyzing the correlation of spinal cord atrophy with regional brain atrophy and corresponding clinical variables.

Results: The spinal cord atrophy happens with aging and is aggravated in neurological diseases, which partly reflects cognitive conditions and physical disability.

Impact: Identifying disease-specific patterns of spinal cord atrophy somehow helps in differential diagnosis and MUCCA could be serve as a MRI marker for cognitive impairment and/or physical disability.

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Keywords