Keywords: Spinal Cord, Neuro, Myelin
Motivation: Discrimination between gray and white matter of the spinal cord remains challenging.
Goal(s): To investigate imaging techniques that best discriminate gray matter from white matter.
Approach: Inhomogeneous magnetization transfer (ihMT) and phase-sensitive inversion recovery (PSIR) have been reported effective in discriminating between gray and white matter. Myelin-sensitive inversion recovery (MySIR) was compared with ihMT and PSIR for evaluating the discriminability between gray and white matter.
Results: MySIR had the highest contrast ratio compared to ihMT and PSIR.
Impact: MySIR was superior to ihMT and PSIR in discriminating gray matter from white matter, and MySIR can be useful as a new myelin-specific MR imaging technique for spinal cord segmentation.
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