Keywords: Diffusion Acquisition, Brain
Motivation: Several multi-shot 2D acquisition techniques have been developed to improve the resolution of diffusion MRI (dMRI) of the brain, but require long scan times.
Goal(s): To develop a 3D dMRI sequence with improved SNR efficiency to achieve high-resolution scans in a reasonable time.
Approach: We implemented a 3D spin echo sequence with an inversion pulse before the excitation to improve SNR at short repetition times and a TURBINE readout trajectory. Projection-based image reconstruction is employed to avoid artifacts caused by shot-to-shot phase errors.
Results: Phantom and human scans at 3T show an improvement in SNR efficiency over 2D dMRI.
Impact: We designed a multi-shot 3D dMRI sequence that is SNR efficient and robust to motion artifacts between shots. This sequence will enable high-resolution diffusion-weighted imaging of the whole brain in short scan times.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords