Keywords: White Matter, Brain, myelin water imaging, Gradient Echo Spin Echo (GRASE))
Motivation: Myelin water fraction (MWF) is conventionally measured using the T2 decay curve. Due to hardware limitations, for spin-echo based sequences, TR and TE times were restricted by SAR and gradient slew rate.
Goal(s): Our objective is to reduce the total scan time by shortening the TR time. A shorter TE time should also capture more signal from the short T2 components of myelin water.
Approach: We implemented myelin water imaging (MWI) on the MAGNUS system with reduced TR and TE times.
Results: When implemented on the MAGNUS system, MWI could be carried out in a shorter time and the MWF were slightly larger.
Impact: The work aims to optimize MWI by shortening scan times. It successfully achieves this, leading to quicker, high-quality MWI acquisition, benefiting medical diagnostics and research efficiency.
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