Keywords: Spinal Cord, Relaxometry, Quantitative Magnetization Transfer, C-spine
Motivation: We proposed to use a method known as selective inversion recovery (SIR), which allows one to perform the entire QMT (quantitative magnetization transfer) experiment from a conventional inversion recovery sequence.
Goal(s): To translate the SIR-QMT method to the spinal cord at 3T with optimized sampling schemes to yield high-resolution cervical spinal cord PSR (macromolecular pool-size-ratios) maps within clinically relevant scan times.
Approach: SIR-QMT was conducted on two healthy volunteers to calculate PSR and R1f.
Results: These results suggest that QMT imaging can be performed in the human cervical spinal cord at 3T.
Impact: The work has important clinical indication to study de/remyelination and nerve injuries/repairs in spinal cord disorders.
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