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Abstract #2585

Estimating pathologic prognostic factors in epithelial ovarian cancers using apparent diffusion coefficients from functional tumour burden

Cheng Zhang1, Yujiao Zhao2, Yue Cheng2, Jiaming Qin3, and Wen Shen2
1The First Central Clinical School, Tianjin Medical University, Tianjin, China, Tianjin, China, 2Department of Radiology, Tianjin First Central Hospital, School of Medicine, Nankai University, Tianjin, China, Tianjin, China, 3School of Medicine, Nankai University, Tianjin, China, Tianjin, China

Synopsis

Keywords: Diffusion Analysis & Visualization, Cancer

Motivation: EOC is highly heterogeneous, meaning the average ADC value of the total tumor cannot reflect its internal components, which vary based on pathology.

Goal(s): This study sought to assess the utility of ADC values from total and functional tumor burdens to determine pathologic prognostic factors in EOC.

Approach: Using k-means clustering to divide the tumor into 2 clusters based on their ADC values, the low ADC cluster was considered to be high cellular. Furthermore, minimum, maximum and average ADC values of functional tumor were calculated.

Results: ADC values derived from functional tumor could be used to assess preoperative prognostic factors in EOC.

Impact: ADC values derived from functional tumor could be used to assess preoperative prognostic factors in EOC.

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