Meeting Banner
Abstract #2591

Test-retest repeatability of intravoxel incoherent motion (IVIM) MRI in the cervical cord at 3T

Anna Lebret1, Simon Lévy2,3,4, Patrick Freund1,5, Virginie Callot3,4, and Maryam Seif1,5
1Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland, 2MR Research Collaborations, Siemens Healthcare Pty Ltd, Melbourne, Australia, 3CNRS, CRMBM, Aix-Marseille Univ, Marseille, France, 4CEMEREM, APHM, Hôpital Universitaire Timone, Marseille, France, 5Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany

Synopsis

Keywords: IVIM, Spinal Cord

Motivation: High precision of intravoxel incoherent motion (IVIM) MRI parameters in the cervical cord can facilitate studies targeting perfusion impairment and substantiate clinical findings.

Goal(s): To determine the test-retest repeatability of IVIM in the cervical cord using four different common model fitting approaches.

Approach: Test-retest cardiac-gated IVIM acquisitions, sensitive to perfusion, were performed at 3T in 10 healthy subjects at C1-C3 levels. Reliability was assessed using relative test-retest differences, within-subject coefficients of variation and intraclass correlation coefficients.

Results: IVIM parameters in the cervical cord showed high repeatability at the group level in the white and grey matter.

Impact: The high test-retest repeatability of IVIM parameters in the cervical cord will help the interpretation of future clinical findings and support its relevance for applications in various neurological diseases affecting the spinal cord.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords